Cathepsin B Market Report -Pipeline Review, H2 2017

“The Latest Resrach Report Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Pipeline Review, H2 2017 provides information on pricing, market analysis, shares, forecast, and company profiles for key industry participants. – MarketResearchReports.biz”

About Cathepsin B Market

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Cathepsin B (CatB) is an enzymatic protein belonging to the peptidase. It promotes hydrolysis of proteins with broad specificity for peptide bonds. It cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates. In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides.

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1) pipeline Target constitutes close to 9 molecules. Out of which approximately 6 molecules are developed by companies and remaining by the universities/institutes. The molecules developed by companies in Phase I, Phase 0, Preclinical and Discovery stages are 1, 1, 3 and 1 respectively. Similarly, the universities portfolio in Preclinical and Discovery stages comprises 2 and 1 molecules, respectively. Report covers products from therapy areas Central Nervous System, Oncology, Gastrointestinal, Immunology and Infectious Disease which include indications Alzheimer’s Disease, Liver Fibrosis, Autoimmune Disorders, Breast Cancer, Cancer Pain, Ebolavirus Infections (Ebola Hemorrhagic Fever), Neuropathic Pain, Non-Alcoholic Steatohepatitis (NASH), Pancreatic Cancer, Primary Biliary Cirrhosis and Traumatic Brain Injury.

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The latest report Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Pipeline Review, H2 2017, outlays comprehensive information on the Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type. It also reviews key players involved in Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1) targeted therapeutics development with respective active and dormant or discontinued projects.

The report is built using data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope

– The report provides a snapshot of the global therapeutic landscape for Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)

– The report reviews Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources

– The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages

– The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities

– The report reviews key players involved in Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1) targeted therapeutics and enlists all their major and minor projects

– The report assesses Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type

– The report summarizes all the dormant and discontinued pipeline projects

– The report reviews latest news and deals related to Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1) targeted therapeutics

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Reasons to buy

– Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies

– Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

– Identify and understand the targeted therapy areas and indications for Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)

– Identify the use of drugs for target identification and drug repurposing

– Identify potential new clients or partners in the target demographic

– Develop strategic initiatives by understanding the focus areas of leading companies

– Plan mergers and acquisitions effectively by identifying key players and its most promising pipeline therapeutics

– Devise corrective measures for pipeline projects by understanding Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1) development landscape

– Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Table of Contents

Table of Contents 2

List of Tables 4

List of Figures 4

Introduction 5

Global Markets Direct Report Coverage 5

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Overview 6

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Therapeutics Development 7

Products under Development by Stage of Development 7

Products under Development by Therapy Area 8

Products under Development by Indication 9

Products under Development by Companies 10

Products under Development by Universities/Institutes 12

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Therapeutics Assessment 14

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Assessment by Mechanism of Action 14

Assessment by Route of Administration 15

Assessment by Molecule Type 16

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Companies Involved in Therapeutics Development 18

ALSP Inc 18

Oncomatryx Biopharma SL 18

Phelix Therapeutics LLC 18

Virobay Inc 19

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Drug Profiles 20

ALP-496-Drug Profile 20

Product Description 20

Mechanism Of Action 20

R&D Progress 20

CIBP-4-Drug Profile 22

Product Description 22

Mechanism Of Action 22

R&D Progress 22

Drugs to Inhibit Cathepsin B for Ebola Viral Infections-Drug Profile 23

Product Description 23

Mechanism Of Action 23

R&D Progress 23

OMTX-001-Drug Profile 24

Product Description 24

Mechanism Of Action 24

R&D Progress 24

Small Molecule to Inhibit Cathepsin B for Oncology-Drug Profile 25

Product Description 25

Mechanism Of Action 25

R&D Progress 25

Small Molecules to Inhibit Cathepsin B for Alzheimer’s Disease-Drug Profile 26

Product Description 26

Mechanism Of Action 26

R&D Progress 26

VBY-285-Drug Profile 27

Product Description 27

Mechanism Of Action 27

R&D Progress 27

VBY-376-Drug Profile 28

Product Description 28

Mechanism Of Action 28

R&D Progress 28

VBY-825-Drug Profile 29

Product Description 29

Mechanism Of Action 29

R&D Progress 29

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Dormant Products 30

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Product Development Milestones 31

Featured News & Press Releases 31

Apr 19, 2016: American Life Science Pharmaceuticals Obtains Patent 31

Jan 25, 2016: ALSP invited to Give Oral Presentation at the Keystone TBI Conference January 25-27 in Santa Fe, New Mexico 31

Nov 14, 2011: Virobay’s Spectrum-Selective Cathepsin Inhibitor Shows Efficacy In Bone Cancer Model 31

Appendix 33

Methodology 33

Coverage 33

Secondary Research 33

Primary Research 33

Expert Panel Validation 33

Contact Us 33

Disclaimer 34

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